U.S. Protein Purification And Isolation Market Size, Share And Trends Report, 2030



Market Size & Trends

The U.S. protein purification and isolation market size was estimated at USD 3.8 billion in 2023 and is expected to grow at a CAGR of 10.7% from 2024 to 2030. The demand for protein purification and isolation is fueled by the increasing research in the pharmaceutical and biotechnology sectors to create new drugs. The market growth is expected to be propelled by pharmaceutical companies' escalating investments in R&D. The pandemic caused disruptions in the market, but with increased government funding for R&D and technological advancement, the market is expected to have significant growth in the forecast period.

Technology Insights

Chromatography dominated the market and held the largest revenue share of 29.27% in 2023 and is expected to grow at the fastest CAGR during the forecast period. This technique is highly accurate and sensitive for protein isolation and purification. As a result, many companies focus on launching new products based on this technology to broaden their product range. For instance, Bio-Rad introduced ChromLab Software in 2018, a unique software for protein purification using NGC chromatography systems. The availability of various chromatography techniques suitable for a wide range of applications further propels the segment’s growth.

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Product Insights

Consumables dominated the market and held the largest share of 61.77% in 2023 and is expected to grow at the fastest CAGR from 2024 to 2030. The broad consumables category includes various commonly used items such as columns, reagents, kits, resins, and magnetic beads. In 2023, the kits segment emerged as the dominant player within the consumable product category. The popularity of kits can be attributed to their convenience and the numerous advantages. One such advantage is their effective use in isolating GST-tagged proteins from either crude or cleared lysate.

Application Insights

Protein-protein interaction studies dominated the market and held the largest revenue share of 32.05% in 2023 due to their crucial role in understanding biological processes and developing targeted therapies. Researchers can uncover disease mechanisms, identify drug targets, and design more effective treatments by investigating how proteins interact. This focus on protein interactions has driven demand for purification and isolation products, especially in academic institutes and research organizations, leading to significant market growth. The emphasis on studying protein-protein interactions reflects a strategic approach to advancing biomedical research and drug development.

Key U.S. Protein Purification And Isolation Company Insights

Key U.S. protein purification and isolation companies are actively participating in product development, innovation, regional expansion, mergers & acquisitions, partnerships, and collaborations to increase their market share. For instance, in August 2021, Danaher Life Sciences acquired Aldevron. After the purchase, Aldevron independently functions under Danaher’s Life Science division while maintaining its original brand identity. This acquisition also signifies an expansion in Danaher’s portfolio in the life sciences sector.

Key U.S. Protein Purification And Isolation Companies:

  • Thermo Fisher Scientific, Inc.
  • Merck KGaA
  • QIAGEN N.V
  • Bio-Rad Laboratories, Inc.
  • Agilent Technologies
  • GE Healthcare
  • Promega Corporation
  • Norgen Biotek Corp.
  • Abcam plc
  • Danaher

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